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Jianmin Fang Selected Research

monomethyl auristatin E

1/2021Open-label, Multicenter, Phase II Study of RC48-ADC, a HER2-Targeting Antibody-Drug Conjugate, in Patients with Locally Advanced or Metastatic Urothelial Carcinoma.
1/2019Monomethyl auristatin E-conjugated anti-EGFR antibody inhibits the growth of human EGFR-positive non-small cell lung cancer.
1/2016An anti-HER2 antibody conjugated with monomethyl auristatin E is highly effective in HER2-positive human gastric cancer.
8/2015A novel humanized anti-HER2 antibody conjugated with MMAE exerts potent anti-tumor activity.

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Jianmin Fang Research Topics

Disease

26Neoplasms (Cancer)
01/2022 - 05/2005
4Breast Neoplasms (Breast Cancer)
01/2022 - 09/2007
3Stomach Neoplasms (Stomach Cancer)
01/2022 - 01/2016
3Neoplasm Metastasis (Metastasis)
01/2021 - 07/2005
3Lung Neoplasms (Lung Cancer)
01/2019 - 01/2013
3Lewis Lung Carcinoma
01/2016 - 01/2013
2COVID-19
05/2022 - 01/2022
2Carcinoma (Carcinomatosis)
01/2022 - 01/2021
2Hepatocellular Carcinoma (Hepatoma)
01/2019 - 01/2016
2Parkinson Disease (Parkinson's Disease)
01/2018 - 06/2016
2Disease Progression
08/2015 - 07/2005
1Colonic Neoplasms (Colon Cancer)
12/2021
1Anemia
11/2021
1Alopecia (Baldness)
11/2021
1Asthenia
11/2021
1Hypesthesia (Numbness)
01/2021
1Neutropenia
01/2021
1Severe Acute Respiratory Syndrome
01/2021
1Leukopenia
01/2021
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2019
1B-Cell Lymphoma (Lymphoma, B Cell)
09/2018
1Choroidal Neovascularization
01/2018
1Hepatitis C
12/2017
1Liver Diseases (Liver Disease)
12/2017
1Sarcoma (Soft Tissue Sarcoma)
05/2017
1Neuroinflammatory Diseases
01/2017
1Hypertension (High Blood Pressure)
01/2017
1Ovarian Neoplasms (Ovarian Cancer)
10/2016
1Neurodegenerative Diseases (Neurodegenerative Disease)
06/2016
1Liver Neoplasms (Liver Cancer)
01/2016
1Rheumatoid Arthritis
01/2016
1Prostatic Neoplasms (Prostate Cancer)
01/2016
1Adenocarcinoma of Lung
01/2016
1Spinal Injuries (Spinal Injury)
10/2015
1Infections
11/2014

Drug/Important Bio-Agent (IBA)

8Monoclonal AntibodiesIBA
01/2022 - 05/2005
8Immunoconjugates (Immunoconjugate)IBA
01/2022 - 08/2015
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2018 - 07/2005
5AntibodiesIBA
05/2022 - 08/2005
5Biomarkers (Surrogate Marker)IBA
01/2022 - 10/2015
4monomethyl auristatin EIBA
01/2021 - 08/2015
4Pharmaceutical PreparationsIBA
01/2019 - 11/2014
4Proteins (Proteins, Gene)FDA Link
12/2017 - 01/2013
3AntigensIBA
01/2022 - 10/2016
3human ERBB2 proteinIBA
01/2022 - 01/2016
3RNA (Ribonucleic Acid)IBA
01/2022 - 04/2014
3ErbB Receptors (EGF Receptor)IBA
01/2019 - 05/2017
3afliberceptIBA
01/2016 - 01/2013
2Immunoglobulin G (IgG)IBA
05/2022 - 03/2011
2Trastuzumab (Herceptin)FDA Link
01/2022 - 08/2015
2VaccinesIBA
01/2022 - 01/2021
2B7-H1 AntigenIBA
12/2021 - 01/2021
2Therapeutic UsesIBA
01/2018 - 03/2011
2Nerve Growth Factors (Neurotrophins)IBA
01/2018 - 06/2016
2Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
01/2016 - 07/2005
1Immunoglobulin M (IgM)IBA
05/2022
1Immunoglobulin A (IgA)IBA
05/2022
1ImmunosorbentsIBA
05/2022
1EnzymesIBA
05/2022
1Immune Checkpoint InhibitorsIBA
01/2022
1disitamab vedotinIBA
01/2022
1EpitopesIBA
01/2022
1Peptides (Polypeptides)IBA
01/2022
1Glycoproteins (Glycoprotein)IBA
12/2021
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
11/2021
1BilirubinIBA
01/2021
1atezolizumabIBA
01/2020
1pembrolizumabIBA
01/2020
1LigandsIBA
01/2020
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2020
1Proto-Oncogene Proteins c-metIBA
01/2020
1CD19 AntigensIBA
09/2018
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
01/2018
1DNA (Deoxyribonucleic Acid)IBA
05/2017
1Cell-Free Nucleic AcidsIBA
05/2017
1Angiotensin IIIBA
01/2017
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2017
1Bispecific AntibodiesIBA
01/2017
1Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2017
1Membrane Proteins (Integral Membrane Proteins)IBA
01/2016
1Tumor Biomarkers (Tumor Markers)IBA
01/2016
1Ado-Trastuzumab EmtansineIBA
01/2016
1serum P-component (CIt)IBA
01/2016
1Antimitotic AgentsIBA
01/2016
1Histones (Histone)IBA
01/2016
1alpha-SynucleinIBA
10/2015
1Cytotoxins (Cytolysins)IBA
08/2015
1monomethylauristatin FIBA
08/2015
1Epidermal Growth Factor (EGF)IBA
08/2015
1Lapatinib (GW572016)FDA Link
08/2015
1Vascular Endothelial Growth Factor CIBA
04/2014
1PyrophosphatasesIBA
11/2013
1Adenosine Triphosphate (ATP)IBA
11/2013
1diphosphoric acid (pyrophosphoric acid)IBA
11/2013

Therapy/Procedure

17Therapeutics
01/2022 - 07/2005
3Immunotherapy
01/2020 - 08/2008
1Molecular Targeted Therapy
01/2022
1Drug Therapy (Chemotherapy)
11/2021
1Aftercare (After-Treatment)
09/2018